Matching names to genes: the end of genetic privacy?

















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Are we being too free with our genetic information? What if you started receiving targeted ads for Prozac for the depression risk revealed by your publicly accessible genome? As increasing amounts of genetic information is placed online, many researchers believe that guaranteeing donors' privacy has become an impossible task.












The first major genetic data collection began in 2002 with the International HapMap Project – a collaborative effort to sequence genomes from families around the world. Its aim was to develop a public resource that will help researchers find genes associated with human disease and drug response.












While its consent form assured participants that their data would remain confidential, it had the foresight to mention that with future scientific advances, a deliberate attempt to match a genome with its donor might succeed. "The risk was felt to be very remote," says Laura Lyman Rodriguez of the US government's National Human Genome Research Institute in Bethesda, Maryland.












Their fears proved to be founded: in a paper published in Science this week, a team led by Yaniv Erlich of the Whitehead Institute in Cambridge, Massachusetts, used publicly available genetic information and an algorithm they developed to identify some of the people who donated their DNA to HapMap's successor, the 1000 Genomes Project.











Anonymity not guaranteed












Erlich says the research was inspired by a New Scientist article in which a 15-year-old boy successfully used unique genetic markers called short tandem repeats (STRs) on his Y chromosome to track down his father, who was an anonymous sperm donor. Erlich and his team used a similar approach.













First they turned to open-access genealogy databases, which attempt to link male relatives using matching surnames and similar STRs. The team chose a few surnames from these sources, such as "Venter",and then searched for the associated STRs in the 1000 Genomes Project's collection of whole genomes. This allowed them to identify which complete genomes were likely to be from people named Venter.












Although the 1000 Genome Project's database, which at last count had 1092 genomes, does not contain surname data, it does contain demographic data such as the ages and locations of its donors. By searching online phonebooks for people named Venter and narrowing those down to the geographic regions and ages represented in the whole genomes, the researchers were able to find the specific person who had donated his data.












In total, the researchers identified 50 individuals who had donated whole genomes. Some of these were female, whose identity was given away because of having the same location and age as a known donor's wife.











Matter of time













Before publishing their findings, the team warned the US National Institutes of Health (NIH) and other institutions involved in the project about the vulnerability in their data. Rodriguez says that they had been anticipating that someone would identify donors, "although we didn't know how or when".












To prevent Erlich's method from being used successfully again, age data has been removed from the project's website. Erlich says that this makes it difficult, although not impossible, to narrow the surnames down to an individual.












"The genie's out of the bottle," says Jeffrey Kahn of Florida State University in Tallahassee. "It's a harbinger of a changing paradigm of privacy." A cultural zeitgeist led by companies such as Facebook has led to more information sharing than anyone would have thought possible back in 2002 when HapMap first began, he says.











Recurring problem













This is not the first time genome confidentiality has been compromised. When James Watson made his genome public in 2007, he blanked out a gene related to Alzheimer's. But a group of researchers successfully inferred whether he carried the risky version of this gene by examining the DNA sequences on either side of the redacted gene.












While someone is bound to find another way to identify genetic donors, says Rodriguez, the NIH believes it would be wrong to remove all of their genome data from the public domain. She says that full accessibility is "very beneficial to science", but acknowledges that the project needs to strike a careful balance between confidentiality and open access.












It is especially pertinent, says Kahn, because genetic data does not just carry information from the person from whom it was taken. It can also reveal the genetic details of family members, some of whom might not want that information to be public. A relative's genome might reveal your own disease risk, for example, which you might not want to know or have an employer learn of. While laws prohibit health insurers and employers from discriminating against people based on their genetic data, it would not be difficult to give another reason for denying you a job.












An individual's relatives could not prevent that individual from learning about themselves, says Rodriguez, but researchers should encourage would-be genome donors to discuss the risks and benefits with their families.

























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Euro gains despite US economic data; yen loses






NEW YORK: The US dollar slipped against the euro Thursday despite encouraging US data on housing and jobs, while the yen slumped to new multi-year lows on speculation of new easing.

The euro benefited from more positive remarks from regional leaders and solid results of a Spanish bond auction, analysts said.

"The Euro rallied to 1.3376 as the European Central Bank and European Union President Herman Van Rompuy stirred hopes of seeing the euro-area return to growth in 2013, but optimism surrounding the single currency may fail to materialize as the debt crisis continues to drag on the real economy," said David Song of DailyFX.

Also helping was strong investor enthusiasm at a US$4.5 billion Spanish bond auction, pushing the troubled government's borrowing costs lower.

At 2200 GMT the euro was at US$1.3375, compared to US$1.3286 late Wednesday.

The US dollar failed to get a boost from a strong fall in weekly jobless claims, a sign of the pace of layoffs, and a rebound in housing starts in December, showing sustained strength in the housing sector.

The yen meanwhile fell to a fresh 30 month low. The dollar topped the 90 yen level briefly before slipping back to 89.86 yen, compared to 88.37 a day earlier.

The euro rose to 120.20 yen, its best level since April 2011, up from 117.42 Wednesday.

David Gilmore of Foreign Exchange Analytics, said speculation was rising that the Bank of Japan could add to stimulus measures in its next policy meeting on January 21-22.

The British pound fell to US$1.5992 from US$1.6006, while the US dollar gained to 0.9322 Swiss francs from 0.9309 francs.

- AFP/jc



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His 2nd term, America's 2nd chance?






STORY HIGHLIGHTS


  • Reeling from the turmoil of the last four years, the country may be ready to regroup

  • President Obama, adopting a more assertive posture, will need to still persuade a divided country to get things done

  • The economy is improving, the nation's demographics are shifting and a new America is emerging




Washington (CNN) -- On the eve of the inauguration, President Barack Obama's second term may also be America's second chance.


The country, in the last four years, has been battered by an economic earthquake while trying to reconcile a debt load threatening to cripple the next generation.


It has been pulled apart by political extremism and the inability to compromise in Washington. The people have been divided -- by demographic shifts, cultural battles and clashes between the rich and the poor, the haves and the have-nots.


So, days before the president's second inaugural, the nation, too, is set to regroup. What it does differently this time around and the decisions the people make, experts say, will speak to the kind of America that emerges during the next four years.


"The enormous promise that everyone felt four years ago, it isn't completely gone but we have diminished our horizons," said Robert Schmuhl, an American studies professor at the University of Notre Dame. "We have learned that we are now living in an era of limits." Obama is perhaps more keenly aware of this than most.


Hope and hurdles


The 44th President was ushered into the Oval Office by a wave of seemingly limitless optimism and buoyed by the historic nature of his presidency as the first African American elected to the lead the free world.


But once in office, he found his efforts to right an economy hobbled by high unemployment -- 10% at its worse in 2009 -- and home foreclosure rates -- one in 29 homes were in foreclosure between 2007 and 2012 -- were limited by the magnitude of the problem and the political realities of a partisan Congress.


His plan to reform the nation's healthcare system further expanded political divides in Washington and helped lead to huge losses among his party's moderates in the 2010 election.








His re-election this fall — due in no small part to demographic shifts that included large numbers of minorities and women — was quickly followed by a protracted and deeply partisan showdown over trimming the nation's debt.


"I think Obama has learned some things," said Curtis Gans, director of American University's Center for the Study of the American Electorate. "He's going to be unlike most second term presidents in that he will be far more assertive than he was in his first term. He will be stronger on pushback against some of the most extreme elements in the Republican House. He's willing to go to battle on the whole concept of getting the economy moving."


The public saw hints of that assertiveness on Monday during a surprise news conference, where he lashed out at Republicans in Congress for playing politics with the debt ceiling.


"We are not a deadbeat nation," Obama said during a nearly hour-long briefing from the East Room of the White House. It a newly combative tone, he called it "absurd" for the federal government not to pay "bills that have already been racked up" and said he will not negotiate "with a gun at the head of the American people."


From Obamacare to the economy to Sandy Hook


Over the next four years, the country will also get a chance to see whether the Affordable Care Act -- or "Obamacare" -- is a positive or negative step for the nation. In 2014, many of the most controversial provisions, including requiring individuals to either participate in a health insurance program or pay a penalty, take effect.


"We will see whether or not we have the strength within ourselves to figure out how we should deal with entitlement programs," Schmuhl said. "In a way, it's a period when the administration will be dealing with problems that are in process."


Obama's ability -- or failure -- to navigate all of this while coming off as a strong, levelheaded leader could help set the nation's tone for years to come.


"If the economy becomes more robust you will have no doubt he will point back and say see that's what I was doing," said Julian Zelizer, a professor of history and public affairs at Princeton University and CNN contributor.


Reagan, Clinton faced similar issues


It's what happened when former President Ronald Reagan, who led the nation at a time when the country was reeling from a tough economy and just starting to get over the Vietnam War. In his second term "there was a sense America was moving in the right direction in terms of how it was doing around the globe," Zelizer said.


When former President Bill Clinton took office the economy wasn't doing well, but by the second term the economy was picking up, allowing him to deliver a balanced budget and ultimate surplus by the end of his presidency.


"There was clearly a shift in the mood," Zelizer said. "In both cases, the presidents were good at claiming credit for it."


Mood matters in the age of austerity


Everyday folks have learned to cut back and suck it up—some after finding themselves underwater on mortgages they could not afford to pay; others after losing jobs that their companies could no longer afford to keep.


So, Americans have been using their credit cards less and paying down debt more -- household debt as a percentage of disposable personal income is at its lowest rate in almost 30 years, according to the Federal Reserve and credit card balances had reached their lowest level in more than a decade.


And many expect the same discipline from their government.


"Americans will be realistic, just as those in government need to be realistic," Schmuhl said of citizens' likely approach to their own finances over the next four years.


But, as Obama enters his second term, both the housing and job markets have been on a slow and steady uptick. Housing sales were up 6% in 2012 -- the biggest gain since 2005, according to CoreLogic -- and the unemployment rate had dropped to 7.8% in December, although there are still 4.8 million Americans -- or 39.1% of the jobless -- classified as long-term unemployed, according to the Bureau of Labor Statistics.


"Going into the second term, the fiscal situation will continue the agenda and the discussion," he said. "It will say a lot about us and where not only the government but the nation might be going. If it is difficult and, shall we say, fractured and there's a sense coming out of it that things are not working as they should my guess is that the public will begin saying: 'When will Washington work on our behalf?'"


Governing on a deadline


That sentiment was foreshadowed in the frustration over the down-to-the-wire, partisan political maneuvering as the last Congress sought to avert the fiscal cliff's steepest domestic spending cuts.


Obama appeared to prevail on that skirmish, delivering on a promise to raise tax rates on wealthy Americans -- although he shifted his definition of "wealthy" from those making $250,000 or more to those making $400,000 and up.


According to Pew Research Center and Gallup polls, Americans were none too impressed with how lawmakers handled the negotiations or the deal that was struck.


Some 41% of those polled disapproved of the deal, according to Pew, and 52% thought the deal would hurt people like them. In the Gallup poll, 67% - disapproved of congressional Republicans' handled the negotiations while 55% disapproved of how Democrats performed.


Still, partly due to deliberate redistricting to protect -- or create -- more partisan congressional districts, American voters continued to elect or re-elect safe representatives to do their bidding in Congress. For instance, most of the 435 members of the House of Representatives -- Republicans and Democrats -- faced little real opposition on Election Day in 2012.


Other battlegrounds: Sequester, gun control, immigration


But the next battle looms. Just weeks after Obama takes his oath of office, a new Congress will be tasked with addressing the automatic spending cuts, or sequester, that were kicked down the road in order to pass a smaller deal at the end of the year.


The new Congress will also consider raising the nation's debt ceiling, or the ability of the U.S. Treasury to borrow money to pay America's bills. Most agree that defaulting on the nation's obligations would be disastrous for America and the global economy, but some Republicans in Congress are starting to hint that they may be prepared to let that happen anyway if large spending cuts are not secured.


And after that, the fight over gun control, a high priority for the White House in the aftermath of the Connecticut school massacre, will pit the president against many members of the House and Senate from safe districts with high ratings and big-dollar donations from gun rights advocates.


The president and vice president unveiled a major plan on Wednesday that included 23 executive actions the president has ordered on his own, while urging the new Congress to take on the meaty issues of an assault weapons ban, limits on the number of bullets a gun magazine can hold, and other sweeping reforms the gun lobby and others say would gut the constitutional right to bear arms.


Immigration reform, another White House priority, will also stoke ideological differences and test the demographic shifts in Congress. For the first time, the House Democratic caucus is dominated by women and racial minorities, while the Republican caucus in that chamber is largely composed of white men. In the Senate, 20 women — the largest number in history — currently hold office.


But women and minorities are far outnumbered and outranked by white males on some of the most powerful congressional committees. And despite several high-ranking exceptions, Obama's Cabinet -- so far -- is shaping up to be largely male and white.


"The first thing we learned is that we're not post-race. That was a lot of willful imagining in '08 that his election would allow us to transcend these questions of race," said Mark Anthony Neal, a cultural and Black studies professor at Duke University. "The American electorate is looking different in terms of race and ethnicity and young folks being engaged. In 2016 our political realities will look more like our demographic realities."


And that's where the nation's shift over the next four years may be most visible.


But look first to the 2014 midterms and then the 2016 presidential election to see if the people signal continued frustration with the current regime -- in Congress and in the White House -- or demonstrate through the power of their vote that they feel the nation has finally turned the corner.







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Manti Te'o kept girlfriend myth alive after revelation

SOUTH BEND, Ind. Not once but twice after he supposedly discovered his online girlfriend of three years never even existed, Notre Dame All-American linebacker Manti Te'o perpetuated the heartbreaking story about her death.




13 Photos


Manti Te'o



An Associated Press review of news coverage found that the Heisman Trophy runner-up talked about his doomed love in a Web interview on Dec. 8 and again in a newspaper interview published Dec. 11. He and the university said Wednesday that he learned on Dec. 6 that it was all a hoax, that not only wasn't she dead, she wasn't real.

On Thursday, a day after Te'o's inspiring, playing-through-heartache story was exposed as a bizarre lie, Te'o and Notre Dame faced questions from sports writers and fans about whether he really was duped, as he claimed, or whether he and the university were complicit in the hoax and misled the public, perhaps to improve his chances of winning the Heisman.

Yahoo sports columnist Dan Wetzel said the case has "left everyone wondering whether this was really the case of a naJive football player done wrong by friends or a fabrication that has yet to play to its conclusion."

Gregg Doyel, national columnist for CBSSports.com, was more direct.

"Nothing about this story has been comprehensible, or logical, and that extends to what happens next," he wrote. "I cannot comprehend Manti Te'o saying anything that could make me believe he was a victim."

On Wednesday, Te'o and Notre Dame athletic director Jack Swarbrick said the player was drawn into a virtual romance with a woman who used the phony name Lennay Kekua, and was fooled into believing she died of leukemia in September. They said his only contact with the woman was via the Internet and telephone.

Te'o also lost his grandmother — for real — the same day his girlfriend supposedly died, and his role in leading Notre Dame to its best season in decades endeared him to fans and put him at the center of college football's biggest feel-good story of the year.

Relying on information provided by Te'o's family members, the South Bend Tribune reported in October that Te'o and Kekua first met, in person, in 2009, and that the two had also gotten together in Hawaii, where Te'o grew up.

Te'o never mentioned a face-to-face meeting with Kekua in public comments reviewed by the AP. And an AP review of media reports about Te'o since Sept. 13 turned up no instance in which he directly confirmed or denied those stories — until Wednesday.

Among the outstanding questions Thursday: Why didn't Te'o ever clarify the nature of his relationship as the story took on a life of its own?

Te'o's agent, Tom Condon, said the athlete had no plans to make any public statements Thursday in Bradenton, Fla., where he has been training with other NFL hopefuls at the IMG Academy.

Notre Dame said Te'o found out that Kekau was not a real person through a phone call he received at an awards ceremony in Orlando, Fla., on Dec. 6. He told Notre Dame coaches about the situation on Dec. 26.




Play Video


Manti Te'o's girlfriend hoax: How did it happen?



The AP's media review turned up two instances during that gap when the football star mentioned Kekua in public.

Te'o was in New York for the Heisman presentation on Dec. 8 and, during an interview before the ceremony that ran on the WSBT.com, the website for a South Bend TV station, Te'o said: "I mean, I don't like cancer at all. I lost both my grandparents and my girlfriend to cancer. So I've really tried to go to children's hospitals and see, you know, children."

In a story that ran in the Daily Press of Newport News, Va., on Dec. 11, Te'o recounted why he played a few days after he found out Kekau died in September, and the day she was supposedly buried.

"She made me promise, when it happened, that I would stay and play," he said.

On Wednesday, Swarbrick said Notre Dame did not go public with its findings sooner because it expected the Te'o family to come forward first. But Deadspin.com broke the story Wednesday.

Reporters were turned away Thursday at the main gate of IMG's sprawling, secure complex. Te'o remained on the grounds, said a person familiar with situation who spoke on condition of anonymity because neither Te'o nor IMG authorized the release of the information.

"This whole thing is so nutsy that I believe it only could have happened at Notre Dame, where mythology trumps common sense on a daily basis. ... Given the choice between reality and fiction, Notre Dame always will choose fiction," sports writer Rick Telander said in the Chicago Sun-Times.

"Which brings me to what I believe is the real reason Te'o and apparently his father, at least went along with this scheme: the Heisman Trophy.

Chicago Tribune columnist John Kass blasted both Te'o and Notre Dame.

"When your girlfriend dying of leukemia after suffering a car crash tells you she loves you, even if it might help you win the Heisman Trophy, you check it out," he said.

He said the university's failure to call a news conference and go public sooner means "Notre Dame is complicit in the lie."

"The school fell in love with the Te'o girlfriend myth," he wrote.

Read More..

Biden Confirms Support for Second Amendment


Jan 17, 2013 6:41pm







gty joe biden mayors nt 130117 wblog Biden Confirms Support for Second Amendment, Says He Owns Two Shotguns

Alex Wong/Getty Images


One day after President Obama unveiled the administration’s plan to curb gun violence, Vice President Joe Biden today defended their intentions, answering critics who have spoken out against the plan for potentially infringing on the Second Amendment rights of Americans.


“The president and I support the Second Amendment,”  Biden said definitively.


Biden, who’s led the task force on gun violence since the December shooting at Sandy Hook Elementary School, noted that he owns guns.


“I have two shotguns, a 20-gauge and a 12-gauge shotgun,” he said. Later in the speech he said his son Beau was a better shot than he is but that is because Beau is in the Army.


Biden spoke today before the annual U.S. Conference of Mayors’ meeting in Washington, D.C. Not everyone in the audience, Biden noted today, agrees with recommendations the White House put forward yesterday. But he defended the administration’s move to push this issue, at one point addressing the roomful of mayors as if he were speaking to them individually, saying that “murder rates in both of our towns are …  well beyond … what’s remotely tolerable for a civilized circumstance.”


“We’re going to take this fight to the halls of Congress,” he said. “We’re going to take it beyond that. We’re going to take it to the American people. We’re going to go around the country making our case, and we’re going to let the voices, the voice, of the American people be heard. ”


Biden again noted that there will not be consensus across the nation, given cultural differences among the states. In many states, he added, hunting is  “big deal.”


But, he quipped, addressing the use of high-capacity magazines in hunting, “As one hunter told me, if you got 12 rounds — you got 12 rounds, it means you’ve already missed the deer 11 times. You should pack the sucker in at that point. You don’t deserve to have a gun, period, if you’re that bad.”


High-capacity ammunition magazines “leave victims with no chance,” Biden said.


He summed up saying, “Recognizing those differences doesn’t in any way negate the rational prospect of being able to come up with common-sense approaches how to deal with the myriad of problems that relate to gun ownership.”


Biden said the “time is now” to make these changes and scoffed at some alternative strategies, like the proposal from the NRA for an armed guard to be placed in every school.


“We don’t want rent-a-cops in schools armed,” he said. “We don’t want people in schools who aren’t trained like police officers.”









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NASA buys blow-up habitat for space station astronauts









































NASA wants to blow up part of the International Space Station – and a Las Vegas firm is eager to help.












The US space agency has signed a $17.8-million contract with Bigelow Aerospace of Nevada to build an inflatable crew habitat for the ISS.












According to details released today at a press briefing , the Bigelow Expandable Activity Module, or BEAM, will launch in 2015. Astronauts on the ISS will test the module for safety and comfort.












BEAM will fly uninflated inside the trunk of a SpaceX Dragon capsule. Once docked and fully expanded, the module will be 4 metres long and 3 metres wide. For two years astronauts will monitor conditions inside, such as temperature and radiation levels.











Bigelow hopes the tests done in orbit will prove that inflatable capsules are safe and reliable for space tourists and commercial research, an idea almost as old as NASA itself. The space agency began investigating the concept of expandable spacecraft in 1958. Space stations like this would be easier to launch and assemble than those with metal components, so would be cheaper. But research ended after a budget crunch in 2000, and Bigelow licensed the technology from NASA.












Stronger skin













The company has made progress, developing shielding that resists punctures from space debris and micrometeorites. BEAM's skin, for instance, is made from layers of material like Kevlar to protect occupants from high-speed impacts. The craft's skin has been tested in the lab alongside shielding used right now on the rest of the ISS, says Bigelow director Mike Gold.












"Our envelope will not only equal but be superior to what is flying on the ISS today. We have a strong and absolute focus on safety," he says.












And we have to be sure that inflatable craft are safe, says William Schonberg, an engineer specialising in orbital debris protection at Missouri University of Science and Technology in Rolla. "The overall risk to the ISS is the sum of the risks of its individual components," he says.












It may seem counter-intuitive, but a flexible, inflatable design is just as likely to survive punishment from space debris as metal shielding, says Schonberg. "Certain composite cloth materials have been shown to be highly effective as shields against [high-speed space] impacts. So depending on what material is used, and in what combination it is used with other materials – such as thermal insulation blankets – the final design could be just as effective and perhaps better than the more traditional all-metal shields used elsewhere on the station."












Gold hopes BEAM will also demonstrate that fabric shielding can limit radiation risks. This is a major worry on missions to the moon or an asteroid say, where astronauts have to spend weeks or months outside Earth's protective magnetic field.












High-energy particles called cosmic rays constantly fly through the solar system, and when they strike metal shielding, they can emit secondary radiation in the form of X-rays. This doesn't happen with Kevlar-based fabric shields and so expandable habitats could be more desirable for travellers heading deeper into space, says Gold.


















































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Cricket: Warne faces new ban






SYDNEY: Australian veteran Shane Warne is facing a new ban for an alleged breach of the spirit of the game in a domestic Twenty20 match, Cricket Australia said Thursday.

The bowling great apologised last week after a foul-mouthed rant against West Indian all-rounder Marlon Samuels that earned him a ban and a fine in Australia's Big Bash League.

But in Wednesday night's semi-final Warne, the official Melbourne Stars skipper, was not listed as captain for the match they lost against Perth Scorchers.

Cricket Australia said they had recently sent a memo to BBL teams about the captaincy role.

"If a team's official captain is selected but not named as captain, this will be considered against the spirit of cricket and may attract a code of behaviour charge," CA said.

"Warne has been reported for breaching CA's code of behaviour," it said.

The time and date of Warne's hearing was yet to be fixed.

The 43-year-old spinner, who was banned for one match and fined A$4,500 over the Samuels row, claimed 708 Test wickets in a celebrated career.

But he has also courted controversy, notably when he was fined for accepting money from a bookmaker and sent home from the 2003 World Cup for taking a banned diuretic.

- AFP/jc



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U.S. regulators ground Dreamliners over fire risk









By Aaron Cooper, CNN


updated 7:32 PM EST, Wed January 16, 2013







This battery was involved in a fire aboard a Japan Airlines Boeing 787 January 7 in Boston.




STORY HIGHLIGHTS


  • NEW: A veteran pilot calls the grounding a prudent move

  • FAA grounds Dreamliners for battery fix

  • The move follows an emergency landing in Japan and another incident in Boston

  • United is the only U.S. carrier to fly the 787 and says it will comply




Washington (CNN) -- U.S. regulators Wednesday ordered airlines to stop flying their Boeing 787s until they can show they've fixed a fire risk linked to battery failures aboard the closely watched Dreamliners.


The move by the Federal Aviation Administration follows an emergency landing in Japan that prompted that country's two major airlines to ground their fleets of 787s, and a similar problem aboard a Dreamliner on the ground in Boston nine days earlier.


"The battery failures resulted in release of flammable electrolytes, heat damage, and smoke on two Model 787 airplanes," the FAA announced Wednesday evening. "The root cause of these failures is currently under investigation. These conditions, if not corrected, could result in damage to critical systems and structures, and the potential for fire in the electrical compartment."


The only U.S. carrier to operate the eagerly awaited, long-delayed jetliner is United Airlines, which said earlier Wednesday that it had inspected its fleet of six 787s and would continue flying them. United spokeswoman Christen David said Wednesday evening that the airline would comply with the order "and will work closely with the FAA and Boeing on the technical review."


The FAA noted that its directive also signals international aviation authorities to take "parallel action" regarding their own airlines.










Since July, the growing list of reported troubles aboard the Dreamliner include a fuel leak, an oil leak, two cracked engines, a damaged cockpit window and a battery problem. The FAA announced a safety review of the aircraft last week.


In the most serious incident so far, an All Nippon Airlines 787 with 129 people aboard made an emergency landing after a battery alarm Wednesday morning. Those on board reported a burning smell in the cabin, and an alarm indicated smoke in a forward electrical compartment.


Hours later, ANA and Japan Airlines announced that they were grounding their Dreamliners pending an investigation. A maintenance worker discovered an electrical fire aboard an empty Japan Airlines 787 slated for departure from Logan International Airport in Boston on January 7.


There was no immediate response from Boeing, which saw its stock take a beating after the incident in Japan. But Boeing chief engineer Mike Sinnett expressed confidence in the battery system after last week's incident in Boston, "I am 100% convinced the airplane is safe to fly. I fly on it all the time."


Asked last week whether he would consider grounding the jets, FAA Administrator Michael Huerta said there was "nothing in the data" that suggested the Dreamliner was unsafe.


Longtime commercial pilot and industry analyst Patrick Smith said the battery issue did not appear to be a major problem, but called the FAA order "a positive and pro-active step."


"I don't think that it was dangerous for the plane to be flying, but it probably wasn't the best thing to be flying it on the heels of this latest emergency landing in Japan," Smith said.


"All airplanes have their teething problems, and this was trending in a bad direction," he added. "Now the authorities have said, 'Stop,' and that's a good thing."


CNN's Mike M. Ahlers and Thom Patterson contributed to this report.








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Manti Te'o says he's the victim of "girlfriend" hoax

Updated 7:23 p.m. ET



SOUTH BEND, Ind. Notre Dame said Wednesday that a story about Manti Te'o's girlfriend dying, which he said inspired him to play better as he helped the Fighting Irish get to the BCS title game, turned out to be a hoax apparently perpetrated against the linebacker.



As news of the alleged hoax spread, Te'o himself released a statement, according to CBSSports.com, saying he as the "victim of what was apparently someone's sick joke and constant lies."

The week before Notre Dame played Michigan State on Sept. 15, coach Brian Kelly told reporters that Te'o's grandmother and a friend had died. Te'o didn't miss the game. He said Kekua had told him not to miss a game if she died. Te'o turned in one of his best performances of the season in the 20-3 victory in East Lansing, and his playing through heartache became a prominent theme during the Irish's undefeated regular season.

Te'o went on the become a Heisman Trophy finalist, finishing second in the voting, and leading Notre Dame to its first appearance in the BCS championship.

Te'o and the Irish lost the title game to Alabama, 42-14 on Jan. 7. He has graduated and was set to begin preparing for the NFL combine and draft at the IMG Academy in Bradenton, Fla., this week.

Te'o's mother did not immediately return a call seeking comment.

The university issued a news release Wednesday after Deadspin.com reported it could find no record of Lennay Kekua existing. It was also announced the university will be having a press conference regarding the story around 9 p.m. ET.

The university statement, according to CBSSports.com, reads in full:



"On Dec. 26, Notre Dame coaches were informed by Manti Te'o and his parents that Manti had been the victim of what appears to be a hoax in which someone using the fictitious name Lennay Kekua apparently ingratiated herself with Manti and then conspired with others to lead him to believe she had tragically died of leukemia. The University immediately initiated an investigation to assist Manti and his family in discovering the motive for and nature of this hoax. While the proper authorities will continue to investigate this troubling matter, this appears to be, at a minimum, a sad and very cruel deception to entertain its perpetrators."



Neither Te'o nor his family has yet commented on the story that has thrown the college football world into a frenzy, reports CBSSports.com.

In reaction to the story, Te'o's teammate, Zeke Motta, tweeted: "My dude @MTeo_5 (Manti Te'o) is as real as it gets... anybody Thinking otherwise needs to check themselves."

Te'o's full statement on the situation, according to CBSSports.com:

"This is incredibly embarrassing to talk about, but over an extended period of time, I developed an emotional relationship with a woman I met online. We maintained what I thought to be an authentic relationship by communicating frequently online and on the phone, and I grew to care deeply about her.

"To realize that I was the victim of what was apparently someone's sick joke and constant lies was, and is, painful and humiliating.

"It further pains me that the grief I felt and the sympathies expressed to me at the time of my grandmother's death in September were in any way deepened by what I believed to be another significant loss in my life.

"I am enormously grateful for the support of my family, friends and Notre Dame fans throughout this year. To think that I shared with them my happiness about my relationship and details that I thought to be true about her just makes me sick. I hope that people can understand how trying and confusing this whole experience has been.

"In retrospect, I obviously should have been much more cautious. If anything good comes of this, I hope it is that others will be far more guarded when they engage with people online than I was.

"Fortunately, I have many wonderful things in my life, and I'm looking forward to putting this painful experience behind me as I focus on preparing for the NFL Draft."



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NRA President Defends Ad Attacking Obama


Jan 16, 2013 6:40pm







ap nra david keene ll 121220 wblog NRA President Defends Ad Attacking Obama, Vows Battle Ahead

Christian Gooden/St. Louis Post-Dispatch/AP Photo


In an interview with ABC News this evening, NRA President David Keene said the gun-rights lobby is aggressively preparing for “battle” with the White House and Congress over President Obama’s sweeping new proposals to curb gun violence.


Keene criticized Obama’s announcement today, surrounded by four children from around the country, for “using kids to advance an ideological agenda.” And he expressed cautious confidence that few of the legislative measures would ultimately pass.


“It’s going to be very tough for the president to accomplish some of these things, but that doesn’t mean he can’t do it if he really turns it on,” Keene told ABC.


“All bets are off when a president really wants to go to war with you,” he said. “We’re gonna be there and we’re gonna fight it.”


INFOGRAPHIC: Guns in America: By The Numbers


Keene said passage of the 1994 assault weapons ban remains fresh in the minds of NRA leaders, noting that initial widespread congressional opposition gradually gave way to a narrow margin in favor, thanks in part to pressure from then-President Bill Clinton.


NRA members would hold accountable any politicians who “sell them out to some pie-in-the-sky scheme such as the president is proposing,” he said.


The group launched a new “Stand and Fight” advocacy campaign Tuesday night, opposing Obama’s gun control measures, anchored by a controversial new TV ad that began airing online and on the Sportsman Channel.


The ad calls President Obama an “elitist hypocrite” for sending his daughters to a private school with armed guards while questioning whether all other U.S. schools should have the same security measures. The White House blasted the ad as “repugnant and cowardly.”


“When the question is the protection of children, which is what this is all about… it’s perfectly legitimate to ask why some children should be protected and other children should not be protected,” Keene said, defending the ad.


“We were not talking about the president’s kids. We were talking about an elite class who criticizes others in their desire to be safe while making sure that they and their families and their children are always protected.


“We’re not talking about the Secret Service protection the president’s children enjoy — they ought to have that wherever they go,” he added.


PHOTOS: Sandy Hook Elementary School Shooting


Keene also ribbed Obama for using children as “props” for his announcement:  “We didn’t line them up on a stage and pat them on the shoulder while we were urging somebody to take our position,” he said.


The NRA has acknowledged some areas of common ground for curbing gun violence included the Obama proposal — namely beefed up resources for mental health care, better background check data and increased presence of school resource officers (police) at public schools.


But Keene said many of those steps were just “fig leaves.”


“What the president did is say … ‘I care about armed security.’ He can check off that box on the Gallup polls. He can say to the people concerned about it, ‘It’s part of my package.’ … He said the problem of severely, mentally ill — we’re going to study it.”


Obama called for federal aid to states for the hiring of up to 1,000 new resource officers and school counselors.  Currently, there are armed resource officers at 28,000 U.S. schools.


“That’s a drop in the ocean in terms of the problem,” Keene said. “It’s simply a fig leaf so he can pursue an anti-gun agenda. It has less to do with security and more to do with gun.”



SHOWS: Good Morning America World News







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